Description
RNA Contamination Removal Magnetic Beads (gDNA Purification)
Genomic DNA extraction is the most popular laboratory technique. However, it is common that the extracted genomic DNA is contaminated with RNA. To reduce the impact on downstream applications, it is critical to purify the genomic DNA by removing RNA contamination.
We have developed a simple reagent to completely remove RNA contamination in the extracted genomic DNA samples based on Solid Phase Reversible Immobilization (SPRI) beads. The magnetic beads are coated with carboxyl groups that can reversibly bind to DNA in an appropriate buffer. Our RNA Contamination Removal Magnetic Beads combines the reversible DNA-binding properties of SPRI magnetic beads with BioDynami’s unique chemistries. The reagent removes the contaminated RNA and recovers the genomic DNA in the same reaction step. Moreover, unwanted components such as proteins, dNTPs, salts, enzymes, and other impurities can also be removed in the same step.
The genomic DNA can be used for downstream applications such as PCR, QPCR, sequencing, microarray, and enzymatic treatment etc. The beads can be an effective and inexpensive reagent for RNA depletion for routine genomic DNA purification.
Features
- Effective removal of RNA contamination by RNase
- Removal of unwanted components and impurities
- High recovery rate of genomic DNA
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