The proprietary CATCH-Seq targeted sequencing technology leverages genomic clones to generate probes corresponding to large, contiguous blocks of a genome such as MHC loci. This is particularly useful when your research calls for sequencing coding and non-coding regions of a gene, including introns and flanking sequences.  Sequencing large target regions including introns make it ideal for identification of structural variants and CNV’s.

CATCH-Seq target enrichment is also ideal for studies of DNA methylation, by performing targeted bisulfite sequencing after the target enrichment steps. CATCH-Seq target enrichment technology is compatible with any NGS library or platform.  Best of all, since CATCH-Seq technology requires no oligonucleotide design and production costs, custom capture reagents are available at a fraction of the cost of other target enrichment methods.