DNA Concentrator (Magnetic Beads)
The DNA Concentrator (Magnetic Beads) can be used to efficiently concentrate DNA/RNA from various samples with low concentration without the need of a DNA vacuum concentrator. Solid Phase Reversible Immobilization (SPRI) magnetic beads are well used for DNA and RNA purification and concentration. The beads are paramagnetic particles coated with carboxyl groups that reversibly bind to DNA and RNA.
The concentrator protocol is simple: mix Concentrator Buffer and Concentrator Beads with the sample, wash, and elute pure DNA in a small volume to concentrate the DNA samples. Moreover, the DNA/RNA samples are also purified during the procedure. The beads with our unique technology purify DNA/RNA samples effectively by removing unwanted components such as dNTPs, enzymes, detergents, proteins, and other contaminants.
However, traditional magnetic beads can only bind nucleic acids that are 100 bp or longer. Nucleic acids shorter than 100 bp are not effectively recovered. We have successfully developed the kit that overcomes the hurdle of short nucleic acids recovery. The reagent can be used for concentration of samples from genomic DNA to short DNA/RNA.
The beads can also be used for size selection of DNA fragments ranging from 150 bp to 800 bp by changing the bead-to-sample volume ratio and performing single or double-size selection. The beads are an ideal choice for NGS library preparation. They can be easily integrated into the standard workflow of NGS library preparation since the volume ratio is similar for protocols using standard magnetic beads.
Features
- Effective concentrator of DNA and RNA samples, even small DNA, RNA, oligos
- Binding capacity: 10 ug DNA per prep
- Removal of unwanted components and other impurities
Recovery Rate
- >90% for DNA size >30 bp
- >80% for DNA size between 20-29 bp
Protocol & MSDS Download
Cat.# & Preps
- Cat.# 40055S: 100 preps
- Cat.# 40055L: 300 preps
Related Products
- Magnetic Beads (DNA & RNA Purification)
- Magnetic Beads (microRNA & Oligo Purification)
- Magnetic Beads (Short Oligo Purification)
- Magnetic Beads (PCR Purification)
- Magnetic Beads (tRNA Purification)
- cfDNA Purification Kit (Magnetic Beads)
- miRNA Purification Kit (tRNA Depletion)
- Plasmid Purification Magnetic Beads (RNA Depletion)
- RNA Contamination Removal Magnetic Beads (gDNA Purification)
- RNase-free RNA Removal (Magnetic Beads)