Epigenetics for analysis of DNA methylation: bisulfite conversion, CpG site detection, methylation-specific PCR, and bisulfite sequencing.

Bisulfite Conversion Kit (Magnetic Beads)

BioDynami Bisulfite Conversion Kit (Magnetic Beads) is available for the detection of genomic DNA methylation using a simple conversion approach. Bisulfite conversion is a standard technique for DNA methylation analysis. The conversion can distinguish methylated cytosines from unmethylated cytosines at single base resolution of genomic DNA.

Bisulfite Sequencing Library Prep Kit

The kit was developed for construction of NGS libraries using bisulfite treated DNA (50 ng – 500 ng) as input. DNA methylation is an epigenetic mechanism known to play a critical role in gene regulation and genomic imprinting by blocking transcription factor access to promoters and enhancers. Bisulfite sequencing is a popular technique in biomedical research based on C to T conversion under the treatment of sodium bisulfite.

Methylation Specific Bisulfite-Seq Library Prep Kit

The kit was developed for construction of NGS libraries for methylated CpG sites using bisulfite treated DNA (20 ng – 500 ng) as input. The kit enriches methylated CpG regions, thus significantly reduce the sequencing cost.