Description
Breast Cancer Panel Targeted Sequencing Kits
The kits were developed for breast cancer genetic testing based on the CATCH-Seq technology. Moreover, kits combining NGS library prep and capture are also available. The integration of library prep and capture simplifies the procedure, and enhances the capture efficiency. Comprehensive sequencing of the 117 breast cancer genes make it possible to detect indels, SNPs, and structural variants that are not covered by other targeted sequencing reagents.
Breast Cancer Panel Capture Kit: Capture reagents only. Library Prep reagents are not included.
Breast Cancer Panel Library Prep & Capture Kit: Combination of library prep reagents and capture reagents.
ABCB1 | BRCA2 | DYNLRB1 | FOXA1 | IGFBP1 | MAPK3 | N4BP2L1 | PIK3CA | SEC16A | TP53 |
ABCG2 | CCND1 | EGF | FUS | IGFBP3 | MAPK8 | NBR2 | PIK3R1 | SERPINE1 | TRIM46 |
AKT1 | CCND2 | EGFR | GATA3 | IL6 | MDM2 | NEK2 | PLAU | SFN | TUSC2 |
APC | CDH1 | EP300 | GDPD3 | INPP5E | MGMT | NME1 | PNMT | SFRP1 | TWIST1 |
AR | CDK2 | ERBB2 | GLI1 | ITCH | MINE1 | NME2 | PPP1R1B | SNAI2 | VEGFA |
ARHGAP9 | CDKN1A | ERBB2 | GPR137 | JUN | MKI67 | NOTCH1 | PTEN | SRC | WEE1 |
ATM | CDKN1C | ERBB3 | GRB7 | KLLN | MLH1 | NPRL2 | PTGS2 | STARD3 | XBP1 |
BAD | CDKN2A | ESR1 | GSTP1 | KRT5 | MMP2 | NR3C1 | PYCARD | TCAP | ZAR1L |
BAP1 | CSF1 | ESR2 | HIC1 | LPAR6 | MMP9 | OVCA2 | RASSF1 | TFF3 | ZMYND10 |
BCL2 | CTNNB1 | FBXO32 | ID1 | MAP1LC3A | MUC1 | PA2G4 | RB1 | TGFB1 | |
BIRC5 | CTSD | FGFR1 | IGF1 | MAP3K1 | MUC16 | PGAP3 | RET | THBS1 | |
BRCA1 | CYB561D2 | FGFR2 | IGF1R | MAPK1 | MYC | PGR | RPL41 | THBS3 |
Our breast cancer panel kits enable the most cost-effective targeted sequencing of the 117 breast cancer genes, including all coding and non-coding regions.
Two index types are available:
Single index: For kits with 24 reactions. Each of the index primers (#1~#24) has a unique 6-base index sequence that can be used to identify libraries. Details about the index can be found here.
Unique dual index: For kits with 96 and 384 reactions. Multiplexing up to 96 libraries is possible. Details about the unique dual index can be found here.
Features:
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- Two options: combination of library prep with capture, or capture alone
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- Simplifies the procedure
- Enhances the capture efficiency
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- Full genomic regions of 117 genes
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- Covers ~9 MB regions
- Covers exons, introns, 5’ regulatory regions, 3’ regulatory regions, and beyond.
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- Easy detection of SNPs, indels, and structural variants
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- The only reagent provides intact sequence information
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- Low cost
- Sample multiplexing: Further reduces the cost
- Two options: combination of library prep with capture, or capture alone
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